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shn-821128 离线
jiangxiaoyu 离线
图上没上皮-间质交界,很难判断侵问(?)(invasion)。 起码CIN 3/carcinoma insitu involving glands. The volume of neoplastic epithelium is very worrisome for invasive cancer. Some low power fields even cannot exclude co-existing glandular neoplasia.
We do diagnose invasive squamous cell carcinoma sometimes even without epithelium-stroma junction. That was when the neoplasitic cells show striking nuclear atypia, abnormal keratinization in cytoplasm and prominent nucleoli. The epithelium shown here doesn't have these features.
zhongshihua 离线