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- 61岁女性,肾肿物.
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liguoxia71 离线
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| 以下是引用Lili0321在2009-1-7 19:55:00的发言： 巢状结构为主，伴少量管状结构，胞核园较一致，未见明显皱缩核（葡萄干核），有中央疤痕，尽管有坏死，肿块较大，还是倾向嗜酸细胞腺瘤。若做电镜检查更好，嗜酸细胞腺瘤内是板层状脊线粒体为主，嫌色细胞癌内有微泡，线粒体是管泡状脊。IHC可做CK7，嗜酸细胞腺瘤多为阴性，嫌色细胞癌多为阳性。 |
谢谢老师.我们也是考虑嗜酸细胞腺瘤.现将IHC传上.CK7是阴性的,但我今天没有拍.明天拍了再上传.
看您的回复,就知道您一定在肾脏病理方面有很深的造诣,不知能不能给我们讲讲肾肿瘤的诊断方面的知识,谢谢.
- 病理，让疾病明明白白。
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stevenshen 离线
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Difficult case to classify and I look forward to hearing the final answer. Thanks.
From morphoogy, it best fit oncocytoma.
Features unusual for oncocytoma - necrosis and focal tubulopapillary area.
Immunostains often not very helpful for cases that are difficult to classify based on morphology.
IHC stains seem to be compatible with oncocytoma, except for CD10+
For practical purposes, my opinion is that it is better classify it as renal cell carcinoma
1) Renal cell carcinoma, unclassfied (comment on necrosis and CD10+)
2) Renal cell caricnoma with combined features of papillary renal cell carcinoma and oncocytoma
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lantian0508 离线
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