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- 65岁，宫颈基底细胞增生？CIN？IHC出来了
There is absolutely no CIN in this case. If you pay attention to original H&E, you will find this is an old lady with likely prolapse-related change with hyperkeratosis and parakeratosis. The hyperplastic change at the basal portion is most likely caused by prolase-related stimulation. The p16 immunostain should be interpreted as negative in this case (just some background staining). If she has HPV test, my bet is that she is likely HPV-negative. So I would render my diagnosis as follow:
- Benign squamous mucosa with prolapse-related change, negative for dysplasia.
- 不坠青云之志，长怀赤子之心
| 以下是引用杨斌在2010-9-21 8:23:00的发言：
There is absolutely no CIN in this case. If you pay attention to original H&E, you will find this is an old lady with likely prolapse-related change with hyperkeratosis and parakeratosis. The hyperplastic change at the basal portion is most likely caused by prolase-related stimulation. The p16 immunostain should be interpreted as negative in this case (just some background staining). If she has HPV test, my bet is that she is likely HPV-negative. So I would render my diagnosis as follow: - Benign squamous mucosa with prolapse-related change, negative for dysplasia. 支持 |
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