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74 year old man with 1.0 cm lung nodule (12052008)

stevenshen 离线

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楼主 发表于 2008-12-06 08:35|举报|关注(0)
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姓    名: ××× 性别:  Male 年龄:  74
标本名称: Lung wedge biopsy
简要病史: Patient has pancreatic mass and lung nodule
肉眼检查: 1.0 cm nodule
Frozen section of lung nodule
  • 74 year old man with 1.0 cm lung nodule (12052008)图1
    图1
  • 74 year old man with 1.0 cm lung nodule (12052008)图2
    图2
  • 74 year old man with 1.0 cm lung nodule (12052008)图3
    图3
  • 74 year old man with 1.0 cm lung nodule (12052008)图4
    图4
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1 楼    发表于2009-03-05 08:07:00举报|引用
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Final diagnosis we rendered is: Adenocarcinoma with mucinous features, favor metastatic carcinoma of pancreas

There is always an error when I try to finalize it! Can someone help?

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2 楼    发表于2009-01-05 05:19:00举报|引用
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Frozen diagnosis: Adenocarcinoma with mucinous features
Final diagnosis: Adenocarcinoma with mucinous features, favor metastatic carcinoma of pancreas
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1. Very difficult to distinguish primary lung and metastatic mucinous adenocarcinoma (pancreatic) based on morphology; therefore do not give a definitive diagnosis of primary site
2. Immunostains cannot help: TTF1 cannot help (often negative), CK7/CK20 doesn't help either
3. In a patient with lung nodule and pancreatic mass, the chance of metastasis is higher than two separate tumors. Ask patient's history and clinical correlation.
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3 楼    发表于2008-12-20 08:47:00举报|引用
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There are no tricks here. Will tell you what I think next week and the final diagnosis. 

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4 楼    发表于2008-12-13 07:11:00举报|引用
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Selective IHC results: CK7(+), CK20 Focal weakly (+), TTF-1(-)

Differential Diagnoses: lung primary or metastatic pancreatic adenocarcinoma

If lung primary, will consider Whipple surgery for pancreatic mass

If panreatic metastasis (stage IV), less likely to perform Whipple

What's the appropriate frozen diagnosis ?

What's the final diagnosis??   

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