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wangxf_1997 离线
stevenshen 离线
It is possible that it is invasive ductal carcinoma and solid DCIS; I would guess that it is LCIS with invasive lobular carcinoma (pleomorphic type). Thanks. Looking forward to hearing the discussion and final answer.
(abin译:这例可能是浸润性导管癌和实性DCIS。我猜也可能是LCIS伴浸润性小叶癌(多形性亚型)。谢谢。期待听到讨论和最终结果。)
以下是引用cqzhao在2008-12-11 2:00:00的发言:
Good analysis. H&E slides are good enough to know the of insitu and invasive carcinoma. The key for this case is the nature of the tumor. I will take some photos when I have time. You can continue to guess. |
分析的好,HE切片足以识别原位癌和浸润癌,这个病例的关键是肿瘤的特性,有时间时,我会采一些图片,
大家继续讨论
闲来看云译
Photos 200x
F1 E-cadherine for insitu ca 图1 原位癌E-cadherin染色
F2 E-cadherine for invasive 图2 浸润癌E-cadherin染色
F3 P120 for insitu ca 图3 原位癌P120染色
F4. P120 for invasive ca 图4 浸润癌P120染色
Ductal ca (or normal ducts): memberane stain for both e-cad and p120
Lobular lesion: Absence of stain for E-cad and strong cytoplasmic stain for p120.
导管癌(或正常导管): E-cadherin和p120均呈膜阳性。
小叶病变:E-cadherin不着色,p120胞浆强阳性。
(abin译)