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59 year old man with mastoid mass (ss112108)

stevenshen 离线

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楼主 发表于 2008-11-22 08:45|举报|关注(0)
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姓    名: ××× 性别:   年龄:  
标本名称:  Mastoid biopsy
简要病史:  
肉眼检查:  1.0x0.8x0.6 cm

Great discussion and comments! I did not include cytology imprint pictures.  I am surprised that nobody is asking for it. Here are two pictures of cytology - it might be useful to narrow down your differential diagnosis and immunohistochemical workup.

  • 59 year old man with mastoid mass (ss112108)图1
    图1
  • 59 year old man with mastoid mass (ss112108)图2
    图2
  • 59 year old man with mastoid mass (ss112108)图3
    图3
  • 59 year old man with mastoid mass (ss112108)图4
    图4
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本帖最后由 于 2008-11-30 05:15:00 编辑
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×参考诊断
Large B cell lymphoma

stevenshen 离线

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1 楼    发表于2008-12-06 08:26:00举报|引用
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Frozen diagnosis: atypical lymphoid proliferation, suspicious for lymphoma

Final diagnosis: Large B cell lymphoma (confirmed by flow cytometry)

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  • For small biopsy, touch prep imprint cytology should always be done before frozen section
  • When suspicious for lymphoma, remember to save tissue for flow cytometric study, permanent H&E section, and other possibel studies
  • Cytologic diagnosis is very valuable adjunct for the correct intraoperative frozen section diagnosis 
  • If possible, get patient's history from the surgeon before or during the surgery 

Please share your interesting frozen cases and lessons!

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stevenshen 离线

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2 楼    发表于2008-11-30 22:12:00举报|引用
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Two photos from intraoperative touch imprint cytology uploaded. They should be helpful. 
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3 楼    发表于2008-11-23 22:22:00举报|引用
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To  2 楼: The answer and comment will be here in 2 weeks.  What's your opinion for this case?
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